Polyaminopropyl Biguanide

Polyaminopropyl Biguanide does not pose much risk other than a slight risk of skin or eye irritation at higher concentrations.

 

 

A Few Companies that use this ingredient:

Although a synthetic ingredient, it is not a terribly dangerous one.  It is not known to be mutagenic on mamilian cells, not an endocrine disruptor, not carcinogenic, and has a low toxicity.  It is not easily absorbed in to skin, and pretty mild on skin and eyes.  One fact that gives me pause is the way in which it works--by breaking the cell wall of the bacteria and damaging its DNA.  Anything that damages DNA doesn't sound very good to me.  However, the studies that have been done on the ingredient have shown that it's not strong enough to break down mamilian cells--so that's a good thing.  The bottom line: although it's not a natural ingredient that I would personally use in our products, if you have to use it (say, in your contact solution) you can breathe a little sigh of relief that it's a safer ingredient.